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Naoki Mine Selected Research

Cdc25C phosphatase (211-221)

9/2017CBP501 inhibits EGF-dependent cell migration, invasion and epithelial-to-mesenchymal transition of non-small cell lung cancer cells by blocking KRas to calmodulin binding.
9/2017CBP501 suppresses macrophage induced cancer stem cell like features and metastases.
9/2014Activation of Nrf2 pathways correlates with resistance of NSCLC cell lines to CBP501 in vitro.
10/2011CBP501-calmodulin binding contributes to sensitizing tumor cells to cisplatin and bleomycin.

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Naoki Mine Research Topics

Disease

4Neoplasms (Cancer)
09/2017 - 10/2011
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2017 - 10/2011
2Malignant Mesothelioma
09/2014 - 10/2011
1Inflammation (Inflammations)
09/2017
1Neoplasm Metastasis (Metastasis)
09/2017

Drug/Important Bio-Agent (IBA)

4Cdc25C phosphatase (211-221)IBA
09/2017 - 10/2011
3Pharmaceutical PreparationsIBA
09/2017 - 10/2011
2Interleukin-6 (Interleukin 6)IBA
09/2017 - 09/2017
2Calmodulin (Calcium-Dependent Activator Protein)IBA
09/2017 - 09/2017
2PlatinumIBA
09/2017 - 10/2011
1Epidermal Growth Factor (EGF)IBA
09/2017
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
09/2017
1CytokinesIBA
09/2017
1Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
09/2017
1Integrin alpha4beta1 (VLA-4)IBA
09/2017
1Conditioned Culture MediaIBA
09/2017
1Heparin-binding EGF-like Growth Factor (HB-EGF)IBA
01/2017
1LigandsIBA
01/2017
1ErbB Receptors (EGF Receptor)IBA
01/2017
1Doxorubicin (Adriamycin)FDA LinkGeneric
10/2011
1DNA (Deoxyribonucleic Acid)IBA
10/2011
1Cisplatin (Platino)FDA LinkGeneric
10/2011
1Bleomycin (Blenoxane)FDA LinkGeneric
10/2011
1Fluorouracil (Carac)FDA LinkGeneric
10/2011

Therapy/Procedure

1Therapeutics
09/2017